Make your vascular younger

Origins of the name “AmealPeptide®
AmealPeptide® is also known as Lactotripeptides. It was named derived from Mongolian words, “ami” meaning life, and “amil” meaning to revive, recover, and fermentate.
AmealPeptide® was discovered over the course of around 40 years of continuous research into the physiological functions of fermented milk, produced during the process of manufacturing the lactic acid drink CALPIS®.
Key features include its blood pressure-lowering effects and ability to improve cardiovascular functions. AmealPeptide® has an inhibitory activity against angiotensin converting enzyme(ACE). It works on blood vessels by inhibiting enzymes that cause elevated blood pressure, thereby minimizing increases in blood pressure, and by stimulating production of nitric oxide (NO), which helps to protect blood vessels.
Lactotripeptides (AmealPeptide®) is certified as a “food for specified health use” (FOSHU) in Japan and has been granted GRAS approval in the US.
AmealPeptide® is an Informed-Choice and Informed-Sport certified raw material and each batch undergoes banned substance testing, which reassures elite athletes and drug tested consumers that the AmealPeptide ingredient does not lead to failed anti-doping tests.

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Brand Story

The lactic acid drink CALPIS® first went on sale in 1919. It originated from cultured milk that Kaiun Mishima encountered in Inner Mongolia.
After 90 years later, it is still part of everyday life for countless people.

Kaiun Mishima
Kaiun Mishima
Kaiun Mishima, the father of CALPIS®

The Birth of CALPIS®

Kaiun Mishima, the father of CALPIS®, went over to mainland China at the age of 25, in 1902. A few years later, he continued on to Inner Mongolia. Exhausted and suffering with ill health after travelling for so long, in 1908 Mishima was given a sour “cultured milk” drink. It was cherished by the local people as the source of their good health, and sure enough restored Mishima to good health too.

Mishima returned to Japan in 1915, at the age of 38. Back home in Japan, he found himself thinking about the cultured milk he had encountered in Inner Mongolia. With help and support from a whole host of people, Mishima took his cue from that cultured milk and dedicated himself to conducting research into Lactobacillus. He eventually came up with a great tasting drink that was quite unlike anything else.

On July 7, 1919, the day of Japan’s Tanabata star festival, a lactic acid drink called CALPIS® went on sale.

Researcher “CALPIS Cultured Milk™”

Research and development of “CALPIS Cultured Milk™”

The lactic acid drink CALPIS® was the starting point for our research and development. We focused on the health benefits of CALPIS® and set out to create a product that would help our customers to stay healthy in body and mind.

As experts in fermented milk and microbiological research, we will continue to explore the limitless possibilities, so that we can keep on providing our unique brand of products and services all over the world.

“CALPIS Cultured Milk™”
The key to health benefits

In 1980, tests on mice revealed that “CALPIS Cultured Milk™”, made from milk and CALPIS® Starter, had the effect of increasing lifespan. In an effort to explain the underlying mechanism and explore new possibilities, we are researching the functional properties of “CALPIS Cultured Milk™”.

●Survival rate of mice after consumption of cultured milk
(K. Arai et al.: Eiyo to Syokuryo, 33, 219-223 (1980))

Effect of “CALPIS Cultured Milk™” on increasing lifespan

Effect of “CALPIS Cultured Milk™” on increasing lifespan

Research and development originating from CALPIS® lactic acid drink

Research and development originating from CALPIS® lactic acid drink



■R&D Center

R&D Center
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■Company outline
Asahi Calpis Wellness Co., Ltd. aims to help customers around the world to lead healthy lives and to improve their quality of life, through unique functional materials that harness the power of nature and through organic microbiological technologies built up over many years of research in areas such as lactic acid bacteria and yeast. To achieve that, we manufacture and sell functional ingredients to corporate customers via our global network.

Name: Asahi Calpis Wellness Co., Ltd.
Head office: 4-1, 2-chome, Ebisu-Minami, Shibuya-ku Tokyo 150-0022, Japan
Division: Functional Food Ingredients Group

■Functional ingredients business
A best seller in Japan, the lactic acid drink CALPIS® is something of a national drink with a history dating back almost 100 years. As experts in fermented milk and microbiological research, focusing on the natural health benefits of CALPIS®, we provide unique, patented functional materials backed up by extensive evidence and a proven safety record. These include AmealPeptide® and Lactobacillus acidophilus L-92™, developed as a result of many years of research. In recent years, we have responded to growing health needs around the world by continually providing valuable information, as well as supplying international customers with our unique functional materials, in an effort to contribute to people’s health all over the world.

■Contact Us
If you have any questions regarding the contents of this website or other such matters, please don’t hesitate to contact us via the following email address.
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

AmealPeptide® and AmealPeptide® logo are registered trademarks of Asahi Soft Drinks Co., Ltd. Use of this site is subject to TERMS & CONDITIONS, PRIVACY POLICY.

CALPIS® is a registered trademark of Asahi Soft Drinks Co., Ltd.